Sunday, August 22, 2010
During my training as a respiratory physician
The review authors say that allergy drops, which patients place under the tongue, might offer effective asthma control with a reduced risk of serious side effects. While widely used in Europe and the United Kingdom, the U.S. Food and Drug Administration has not yet approved "sublingual immunotherapy."
"During my training as a respiratory physician, I was taught that this was a potentially dangerous form of therapy that was of no benefit in asthma, Abramson said. "I personally have changed my views since working on this series of reviews."
The review discloses that Abramson received an honorarium from Boehringer Ingelheim for speaking at the Airways 2006 meeting. He also received a grant from Reckitt Benckiser for a study of NSAID-induced asthma.
Abramson MH, Puy RM, Weiner JM. Injection allergen immunotherapy for asthma. Cochrane Database of Systematic Reviews 2010, Issue 8.
Friday, June 11, 2010
Here are the exact steps for finding the right spot to pinch
accurate skinfold with the Accu Measure calipers
1. Holding the Accu measure in your right hand in "pinch-ready" position, reach
across your body with your left hand and locate the proper skinfold site by
taking your left index finger and putting it on the top of your right hip bone
(That's the "Illiac crest). This is the anatomical landmark you must find before
you take the measurement. Don't just grab randomly without locating the spot
first - it's extremely important to grab the same place every time. One inch
up, down, left or right and your measurements will be inconsistent.
2. Leaving your left index finger on the spot, take your left thumb and pinch the
skinfold firmly between your left thumb and index finger.
3. Without letting go of the skinfold, clamp the caliper onto the middle of the
skinfold using your right hand. As you close the caliper, the plastic slide-rule
will move until the point where the Accu measure "clicks" – that's when you
know your measurement is done. Then, release the caliper jaws and look at the
calipers to see where the black line on the slide rule is pointing. That number is
your lliac crest skinfold thickness in millimeters.
4. When you're just starting out, I recommend taking three measurements. If
they're all the same, (i.e, 13, 13, 13) then your accuracy was good and that's
your measurement. If they're close, take the average of the three (example,
14, 13, 13.5 = average of 13.5 mm). If your measurements "all over the map"
(19 mm, 11 mm, 15 mm), your technique is off and you need some practice!
Don't give up - keep working at it.
5. Record the SINGLE measurement at the illiac crest once per week. Measure to
the half of a millimeter: If the black line on the slide rule points to between 12
and 13, write down 12.5 millimeters as your measurement.
6. You now have your skinfold thickness in millimeters. To translate that number
into a body fat percentage, look at your skinfold interpretation chart. The chart
that comes with the Accu measure caliper is fine, but to avoid making the chart
huge and cumbersome, it only lists skinfolds within a 2 mm range. Therefore
the original Accu measure chart may over or under estimate your body fat. I
wanted more precision, so one day, I took it unto myself to crunch some
numbers and improve the chart. My "expanded" Accu measure skinfold
interpretation chart has taken the data from the original chart and extrapolated
it to the half millimeter in skinfold thickness and it gives you a body fat
Wednesday, June 9, 2010
What Is the Spinal Cord?
The spinal cord extends from the brain and serves mostly as a relay
station connecting the brain to the rest of the body. For protection, the
human spinal cord is encased by bony vertebrae. The region of the spinal
cord closest to the brain connects the brain to regions of the body in that
proximity. This would include the chest and arms. Moving further down
the spinal cord and away from the brain, you begin to find the intercon-
nections between the central nervous system and the lower portions of
our body, such as our legs. However, because the nerve links extending
from the lower extremities must move through the upper regions of the
spinal cord in order to connect with the brain, damage to the upper
region of the spinal cord will affect the lower as well as the upper areas
of our body. Thus, if damage occurs lower in the spinal cord it may result
in temporary or permanent paralysis of only the lower extremities.
However, if the spinal cord is damaged higher up, it can result in paralysis
of both lower and upper extremities.
When you would like to move a particular body part, the process (idea)
originates in the brain in a region called the motor cortex. Motor means
movement! Once initiated, the impulse is carried along a linkage of nerve
cells to the skeletal muscle responsible for moving the limb or body part
that is to move. Incredibly the whole process only requires a couple
neurons linked in series connecting the motor cortex of the brain to the
muscle and occurs in a fraction of a second.
While the motor cortex of our brain is busy sending signals to our
skeletal muscle, signaling it to move, another region of our brain is evalu-
ating and refining the movement. This region is called the cerebellum,
which is behind and lower than the more recognizable parts of the brain.
It is also this region of the brain that is particularly sensitive to the effects
of alcohol and explains why movement becomes less refined when we are
intoxicated.
Sunday, June 6, 2010
How Do Molecules Interact with One Another?
Molecules in our body, or anywhere else in nature, mingle among one
another. And, if things are right, they can interact. When molecules inter-
act the process is called a chemical reaction. For instance, in the reaction
below, A and B are substances that react and are called reactants. As a
result of this chemical reaction, different substances are produced and are
called products. In the chemical reaction below the products are C and D.
A+B→C+D
or
6CO2 + 6H2O → C6H12O6 + 6O2
In a more realistic reaction, carbon dioxide (CO2) reacts with water
to form carbohydrate (C6H12O6) and oxygen (O2). Look familiar? It
might, since it is photosynthesis, the process whereby plants make
carbohydrates.
The reaction arrow (→) separating the reactants and products merely
shows which way the chemical reaction will proceed. A reaction may
proceed in only one direction or it may be reversible, whereby the reac-
tion will proceed in either direction. A reversible-reaction arrow looks
like you might expect (↔). If there is a number (coefficient) in front of
reacting or produced substances this merely tells us how many molecules
of a substance must react or be produced in order for the chemical reaction
to make sense or to be "balanced."
In chemical reactions, molecules can react to form new molecules.
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Wednesday, May 19, 2010
My excess
Up to then I had led a fairly conventional social and professional lifestyle and my tendency to put on weight had seemed to level off. My"overeating", if indeed I overate at all, was only very occasional and tended to occur in a family context. When you come, as I do, from South West France, you have been brought up to value gastronomic cuisine as part of your cultural heritage. I had long since given up sugar, or at least, sugar in coffee. I never ate potatoes, claiming to be allergic to them, and, apart from wine, very rarely touched alcohol.
My excess stone had been acquired over a period of ten years, quite gradually. When I looked around me I felt no more overweight than the average; in fact, it seemed to me I compared quite well with other people.
Then, overnight, my professional circumstances changed. I was appointed to a new post with an international dimension at the European headquarters of the American multinational company I worked for.
From then on, much of my time was spent travelling, and the visits to the company's subsidiaries that my responsibilities entailed making were inevitably punctuated with lavish meals.
Back in Paris, my responsibility for public relations involved me in taking mostly foreign visitors to the best French restaurants in the capital. It was simply a part of my job but, I have to admit, not exactly the part I dreaded most.
But three months after taking up my new post I had put on no less than a further stone. It has to be said that the three-week training course I had completed in England had done nothing to help matters either. At any rate, alarm bells were ringing, and urgent action was called for.
Thursday, May 13, 2010
Your body in anyone other than in the hands of a professional
A good method to see if your spine might be out of alignment is to periodically take the measurements of each of your legs. If you notice a difference between the two legs, it would be a good idea to see a chiropractor. He or she will then be able to locate where you are out of alignment and adjust your body as necessary. It is important to note that you should never take chances when it comes to re-aligning your body by seeking help from a friend or family member.
When it comes to your back, do not place your body in anyone other than in the hands of a professional. An error in misalignment could not only make your current problem worse, but could contribute to others as well.
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Tuesday, March 30, 2010
CHROMIUM This mineral is vital in the synthesis of glucose
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Saturday, March 27, 2010
Panax ginseng
Panax ginseng Dosing
The below doses are based on scientific research, publications, traditional use, or expert opinion. Many herbs and supplements have not been thoroughly tested, and safety and effectiveness may not be proven. Brands may be made differently, with variable ingredients, even within the same brand. The below doses may not apply to all products. You should read product labels, and discuss doses with a qualified healthcare provider before starting therapy.
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Sunday, March 14, 2010
Broccoli HELP back pain
Roughly 8 out of 10 people suffer from back pain at some point during their lives. Women, in particular, are prone to posture and back problems—thanks to toting around outrageously heavy purses, going through pregnancy, or giving one-hip rides to kids. Whether you're in the midst of fighting the ache or just want to prevent it, here are some expert-endorsed quick-and-easy ways to wage your war.
You know that calcium is key for strong bones, but Japanese researchers have identified something else you need: vitamin K. It's believed that the vitamin, found in broccoli, spinach, and other dark leafy greens, helps calcium deposit in the bones, making them denser. The stronger your bones, the stronger your whole body—and the lower your chances of an injury that could cause back pain.
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Thursday, March 11, 2010
Children inherit about 30 changed genes from each parent
Children inherit about 30 changed genes from each parent, fewer than had been thought, according to a first detailed look at the blueprint for human life in a family.
Yet that was enough to pass on an inherited illness in that family. And a separate study of an individual genome located the cause of another inherited disease.
That blueprint for life, called DNA, contains about 22,000 genes and researchers calculated the number of changes by analyzing the genes of a mother, father and their son and daughter.
The result, reported in Thursday's online edition of the journal Science, found that the children had about 30 mutations from each parent for a total of 60 changes passed along to the offspring.
Scientists had previously thought a child had about 75 mutated genes from the parents.
The rate probably will vary somewhat, depending on the age of the parents, said co-author Lynn B. Jorde, chairman of the Department of Human Genetics at the University of Utah School of Medicine.
Most mutations are thought to be unimportant, but the rate at which things change is considered critical, helping explain the gradual development of changes.
Jorde and the senior author David J. Galas of the Institute of Systems Biology in Seattle, Washington, studied a family in which the parents had no genetic abnormalities, but each carried recessive genes that resulted in their son and daughter being born with two extremely rare conditions -- Miller's syndrome and primary ciliary dyskinesia.
Miller's syndrome, which causes facial and limb malformations, has been diagnosed in only two families in the world. PCD is a condition in which the tiny hair-like structures that are supposed to move mucus out of airways in the lungs do not function. The chances of having PCD are estimated at one in 10,000.
Jorde said the odds of someone having both PCD and Miller's syndrome are less than one in 10 billion.
"We were very pleased and a little surprised at how much additional information can come from examining the full genomes of the same family," Galas said in a statement.
"Comparing the sequences of unrelated individuals is useful, but for a family the results are more accurate. We can now see all the genetic variations, including rare ones, and can construct the inheritance of every piece of the chromosomes, which is critical to understanding the traits important to health and disease," he said.
The family was not named in the report.
Meanwhile, a separate report in the New England Journal of Medicine disclosed that Dr. James Lupski of Baylor College of Medicine in Texas had sequenced his own complete genome and identified the gene involved in his form of Charcot-Marie-Tooth syndrome, which affects the function of nerves in the body's limbs, hands and feet.
Lupski, vice chairman of molecular and human genetics, said the work "demonstrates that the technology is robust enough that we can find disease genes by determining the whole genome sequence. We can start to use this technology to interpret the clinical information in the context of the sequence -- of the hand of cards you have been dealt."
"Isn't that the goal or dream of personalized genomic medicine?" he said in a statement.
Lupski said he has known for 40 years that he had a disease caused by recessive genes. Now he knows the gene at fault.